We collaborate with scientists to produce peer-reviewed papers by leveraging our analytics infrastructure and expertise.
Anoctamin-5 related muscle disease: Clinical and genetic findings in a large European cohort.
In this study, we supported an international neurology consortium, headed by the Claeys lab, with characterizing genotype-phenotype correlations in a large retrospective cohort of limb-girdle muscular dystrophy patients.
Molecular Cancer 2023
Molecular differences of angiogenic versus vessel-co-opting colorectal cancer liver metastases at single-cell resolution.
In this study, the Conradi lab used Unicle’s UniApp to perform an integrative single cell and spatial analysis to characterize molecular differences in colorectal cancer liver metastases with a desmoplastic versus replacement histopathological growth pattern. The Conradi lab made their data and analysis publicly available via an interactive data portal.
Unraveling the Molecular Basis of the Dystrophic Process in Limb-Girdle Muscular Dystrophy LGMD-R12 by Differential Gene Expression Profiles in Diseased and Healthy Muscles.
In this study, we characterized gene expression networks in muscle biopsies of 84 limb-girdle muscular dystrophy patients and healthy controls.
Comprehensive characterization of the prostate tumor micro-environment identifies CXCR4/CXCL12 crosstalk as a novel antiangiogenic therapeutic target in prostate cancer.
In this collaborative study, the Pircher-Heidegger group used Unicle’s UniApp in an integrative single cell approach to profile the prostate tumor micro-environment to identify novel therapeutic targets for anti-angiogenic therapy. The lab made their data and analysis publicly available via an interactive data portal.